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Cannabigerol (CBG) is one of the many compounds in cannabis plant. Though minor, it is referred to as the mother of all cannabinoids. The reason is that its acidic form forms other cannabinoids when heated. CBG is available in formulations such as oils and gummies. Like CBD, it boasts therapeutic benefits such as pain relief, anxiety alleviation, and improving gut health.
CBG, also known as Cannabigerol, is one of the numerous chemical compounds present in the cannabis plant. It is considered the 'mother' of all cannabinoids. The acidic compounds form CBG-A breaks down to produce other cannabinoids, such as Cannabidiol (CBD), tetrahydrocannabinol (THC), Cannabigerol (CBG), and Cannabichromene (CBC) when heated. It is available in multiple formulations, including but not limited to edibles (gummies) and oils. Unlike THC, CBG is non-psychoactive, meaning it cannot produce a high effect.
CBG products are available in three formulations:
Full spectrum CBD products contain all cannabinoids (CBC, terpenes, flavonoids, CBD) in the cannabis plant, including THC. However, it is worth noting that THC is available in insignificant amounts, not enough to cause any mind-altering effects. It is the most potent thanks to the entourage effect, whereby all the other cannabinoids work synergistically with CBG to boost its therapeutic benefits.
Broad spectrum CBG features CBG and other chemical compounds like terpenes and flavonoids. However, it is free from THC. These products are a great choice for individuals who want to benefit from the effects of other cannabinoids, excluding THC.
CBG isolate products, as its name suggests, solely have CBG. All the other chemical compounds were extracted during extraction, leaving CBG solely. These products allow the user to reap the therapeutic benefits of CBG solely.
Unfortunately, there is no standard dosing size for CBG oil. Its dosage varies with age and cannabis experience. However, the rule of thumb is to begin low and slow; This helps the body get used to the new substance and adjust accordingly. Once the body tolerates it, you may increase your way up gradually until you find your desired effects.
Below are outside factors that may influence your dosage:
Depending on the product formula and CBG strain, you may experience varying ratios of CBG and other cannabinoids in either Full spectrum broad spectrum CBG oil.
Liver metabolism refers to the rate at which the liver breaks down compounds. Also, it is affected by individual genetics. The rate at which your liver metabolizes CBG oil affects the amount you should consume.
The amount of CBG oil you decide to take also depends on the condition to be addressed. Some conditions, such as mental focus support, may require you to take low amounts of CBD oil, while others, such as alleviating stress, may require higher amounts.
CBG, short for Cannabigerol, is one of the numerous chemical compounds in the cannabis plant. However, unlike THC and CBD, it is available in low concentrations. It is referred to as the mother of all cannabinoids since CBG-A, its acidic form, breaks down to other cannabinoids such as CBG, CBD, CBC, and THC when heated. Though it was discovered around 1964, little is known about the compound. However, so far, what is known is that it offers multiple therapeutic benefits.
Its pain-relieving properties may be more potent than THC. Its interaction with the CB1 and CB2 receptors influences heat sensitivity and pain sensation. Additionally, it also boasts anti-cancer and antibacterial properties.
What is CBD?
Cannabidiol (CBD) is one of the most prevalent chemical compounds in the cannabis plant. CBD has multiple properties, such as anti-nausea, anti-fungal, anti-oxidant, and anti-inflammatory, that adds to its numerous therapeutic benefits. It has gained traction amongst multiple cannabis users not only because of its therapeutic benefits but also due to its non-psychoactive nature. Like CBG, it also interacts with the ECS receptors.
These two cannabinoids have varying molecular structures though they have similar therapeutic qualities. Molecular structure affects how the compound binds to the CB1 and CB2 receptors, impacting its bioavailability. These two chemical compounds also have varying effects on appetite. CBG stimulates appetite, while CBD may decrease it.
CBG acts as a neuroprotectant; it boosts memory and focus. Its interaction with the brain's receptors increases neuron reproduction, enhancing greater capacity for an individual to concentrate and focus.
Users report an increased appetite after consuming cannabis products. However, Unlike THC, which leaves individuals yearning for more junk food, CBG makes the user crave more healthy food such as vegetables.
Glaucoma is an eye condition that may lead to blindness, especially for older individuals. Choi et al.(2020) commented that CBG oil binds to these receptors, reducing eye pressure which predisposes patients to glaucoma.
Like CBD, CBG also helps reduce stress and anxiety. Science points out that it may be more effective in alleviating stress compared to CBD. According to Brierley et al. (2016), CBG binds to the ECS receptors increasing the production of dopamine and serotonin hormones, commonly referred to as the feel-good hormones. Additionally, it reduces Cortisol production; the Cortisol hormone is responsible for negative mood.
CBG oil helps manage various inflammatory channels in the immune system. As a result, it reduces pain and inflammation. Kogan et al.(2021) noted that CBG possesses anti-inflammatory and analgesic properties making it a great remedy for treating arthritis and chronic pain. The cannabis derivative also alleviates gut inflammation for users with ulcerative colitis.
Calapaiet al.(2022) suggested that, Since CBG oil is a potent anti-inflammatory and anti-anxiety agent, it indirectly helps improve sleep. Consuming CBG oil a few hours before bedtime helps you relax deeply, making you sleep better. A particular study demonstrated its sedative properties. Its effects on the Cortisol hormone, also known as the stress hormone, lead to deep relaxation, facilitating quality and better sleep.
CBG oil has stress-reducing and anti-anxiety properties like CBD oil. Its interaction with the ECS receptors releases feel-good hormones like dopamine and serotonin, which alleviate anxiety. The cannabis derivative also reduces the production of the Cortisol hormone responsible for negative feelings.
The endocannabinoid system is a complex signaling system in the body. It comprises two specific cannabinoid receptors, CB1 and CB2. The receptors signal primary body functions such as pain, memory, sleep, and appetite. CBG interacts with these receptors to relieve pain relief and suppress anxiety.
CBG and CBD are cannabinoids found in the cannabis plant. However, CBD is found in higher amounts, while CBG is present in lower amounts. Regarding therapeutic benefits, CBG is preferable for treating migraines and muscle soreness, while CBD is more effective in pain and inflammation.
CBG has several side effects, including, but not limited to, sleepiness. However, fewer users have reported sleepiness as a side effect. CBG helps improve sleep by reducing stress and pain.
Similar to CBD, CBG is legal in the UK. However, its THC levels do not exceed 0.2%.
CBG does not contain THC, the compound responsible for the high effect. As a result, it is completely safe and legal to consume since it does not produce a high effect.
Most users consume high amounts of CBG oil without experiencing any side effects. However, for some, if taken in a higher dose, it may cause mild side effects similar to that of CBD.
Some of its possible side effects include:
So, before taking CBG oil, communicate with your doctor to know the ideal dosage. Also, users should purchase the product from reputable brands.
CBG has anti-anxiety properties that reduce anxiety. It increases the production of dopamine and serotonin hormone; it reduces Cortisol hormone release. Resulting in low anxiety levels.
CBGA has energy-boosting qualities like caffeine. However, it is not a stimulant. The cannabis derivative helps increase focus and concentration.
CBG is free from THC, the compound responsible for the high effect. As a result, it does not produce psychoactive responses. Instead, it increases focus and concentration.
Most drug tests check for the presence of THC. CBG is free from THC. As a result, it will not show up on a drug test. Though full-spectrum CBG products might have traces of THC, that amount is not enough to show up on a drug test.
CBG has anti-depressant properties; it increases serotonin levels. As a result, it helps tackle mental health conditions such as stress, depression, and anxiety.
CBG helps reduce fatigue and anxiety and improves energy and attention levels. These effects are useful for clients with ADHD.
CBG has been proven to help with depression. The cannabis derivative increases the production of feel-good hormones such as dopamine and serotonin; it reduces Cortisol hormone levels; these properties work for users with depression.
CBG contains anti-anxiety, anti-inflammatory, and analgesic properties. As a result, it relieves pain and anxiety; the cannabis derivative also increases focus and memory, improves sleep quality, and treats glaucoma.
CBG interacts with the endocannabinoid system receptors; it modulates the production of its neurotransmitters; this improves mood and creates a sense of relaxation and calmness.
CBG is non-intoxicating; it cannot produce a high effect. However, it causes mood elevation and increases concentration. On the other hand, CBN produces mild intoxicating effects; if you consume a higher amount, it may make you high.
There is no standard time on how long CBG gets out of the system. Factors such as BMI and body metabolism affect this duration. For example, users with higher body metabolism clear the product from their systems much faster than their counterparts with sedentary lifestyles.
CBG gummies are chewy candy-like products infused with CBG oil as their main active ingredient. They are available in three formulations: full serum, broad spectrum, and isolate. The cannabis-based gummies offer therapeutic benefits, including but not limited to pain relief and anxiety.
Blundell et al.(2022) stated that CBG has anti-anxiety properties that are helpful for people with PTSD. Its calming and relaxing properties improve sleep quality for patients with PTSD.
Though CBG is non-toxic, it may cause headaches and other side effects such as drowsiness, changes in appetite, and dry mouth if taken in high amounts.
According to Nachnaniet al.(2021), CBG helps with inflammatory bowel syndrome (IBS) due to its pain-relieving properties. It is also a potent anti-oxidant agent, helping alleviate intraocular pressure.
Due to its non-psychoactive nature, CBG is considered to be more of an indica. Additionally, it has effects such as changes in appetite and relaxation, making it similar to a cannabis indica strain.
CBG antagonizes ECS receptors and inhibits GABA functions; it, therefore, helps relieve neuropathic pain. Also, it has anti-inflammatory and analgesic properties that are helpful for users with neuropathic pain.
Full-spectrum CBD features all the other cannabinoids in the cannabis plants, such as THC, CBC, CBD, and CBN. It also contains CBG, which allows it to have a more pronounced entourage effect; the effects describe a situation where many compounds work synergistically to increase therapeutic benefits.
CBG exerts anti-inflammatory effects, which could reduce stomach inflammation. It also helps tackle other stomach issues, such as inflammatory bowel disease.
CBG has antibacterial and anti-inflammatory properties, which help improve gut health. It also helps fight against bacteria that lead to intestinal inflammation.
CBG possesses antibacterial and anti-inflammatory properties, in turn improving digestive health. Studies show that CBG minimizes gut motility for people with inflammatory bowel syndrome.
CBG aids improve IBD symptoms by importing intestinal inflammation and reducing intestinal permeability, helping digestion. The cannabis derivative antagonizes the cannabinoid receptors, which helps alleviate inflammation and benefit the digestive system. Its analgesic properties also help alleviate pain caused by improper digestion.
Though available in fewer amounts, CBG is gaining traction among cannabis users. It is non-psychoactive and may be potent in some areas more than CBD and THC. Its interaction with the ECS provides multiple therapeutic benefits. However, when taken in larger amounts, it may cause various side effects. Hence, you should consult a doctor before taking CBG to help you find the ideal amount. Good-quality products are also vital for reducing the adverse effects of CBG consumption.
Blundell, R., &Gieleta, A. W. (2022). Is cannabis a miracle plant?.
Brierley, D. I., Samuels, J., Duncan, M., Whalley, B. J., & Williams, C. M. (2016). Cannabigerol is a novel, well-tolerated appetite stimulant in pre-satiated rats. Psychopharmacology, 233(19), 3603-3613.
Calapai, F., Cardia, L., Esposito, E., Ammendolia, I., Mondello, C., Lo Giudice, R., ... &Mannucci, C. (2022). Pharmacological Aspects and Biological Effects of Cannabigerol and Its Synthetic Derivatives. Evidence-Based Complementary and Alternative Medicine, 2022.
Choi, S., Huang, B. C., &Gamaldo, C. E. (2020). Therapeutic uses of cannabis on sleep disorders and related conditions. Journal of Clinical Neurophysiology, 37(1), 39-49.
Kogan, N. M., Lavi, Y., Topping, L. M., Williams, R. O., McCann, F. E., Yekhtin, Z., ... &Mechoulam, R. (2021). Novel CBG derivatives can reduce inflammation, pain and obesity. Molecules, 26(18), 5601.
Nachnani, R., Raup-Konsavage, W. M., &Vrana, K. E. (2021). The pharmacological case for cannabigerol. Journal of Pharmacology and Experimental Therapeutics, 376(2), 204-212.
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