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How to Vape CBD Isolate

December 19, 2022 6 min read

How to Vape CBD Isolate

How to Vape CBD Isolate

If you are looking for a comprehensive guide on vaping CBD isolate, you are definitely at the right place. Read on to learn more about CBD vapes, e-liquids, how to vape CBD isolate, and the benefits of vaping CBD isolate.

CBD has gone mainstream, attracting the attention of younger and older folks due to its therapeutic benefits. Furthermore, it is a natural chemical compound with minimal side effects. CBD is available in various forms, including gummies, capsules, tinctures, and vapes. CBD vapes are infused with an e-liquid that is converted into vape and inhaled into the lungs. The e-liquid offers a higher bioavailability since it does not have to be processed by the digestive system, and thus it bypasses first-pass metabolism in the liver. While shopping for CBD e-liquids and vapes, it is important to consider the CBD potency, its safety, and the merits of vaping CBD isolate.

Analysing CBD: Is the Juice Worth the Squeeze?

CBD isolate is a type of CBD that has no other chemical compounds and cannabinoids besides CBD. Therefore, it is considered the purest type of CBD. However, it is important to understand how to obtain CBD isolate by diving deeper into cannabidiol.

CBD is an organic, non-psychoactive chemical compound obtained from hemp. Therefore, as often presumed, it does not cause any 'high' effects. Hemp is a plant strain of the cannabis plant, just like marijuana. However, it has different chemical properties and effects since it does not cause euphoric effects but instead relieves anxiety and stress.

CBD is among a group of hundreds of other chemical compounds known as cannabinoids, which include tetrahydrocannabinol (THC), cannabigerol (CBG), and cannabichromene (CBC). THC is abundant in marijuana and is responsible for the 'high' sensations experienced after consuming cannabis.

CBD is available in various types and potencies. For example, full-spectrum CBD contains various cannabinoids and chemical compounds, including CBG, terpenes, and traces of THC. However, THC levels are low (below 0.2%) to prevent any psychoactive effects.

Broad-spectrum CBD is similar to full-spectrum CBD. However, it lacks THC since it is extracted from it. CBD isolate is the purest form of CBD since it lacks other cannabinoids and only contains CBD as its primary chemical compound. It causes no psychoactive effects and does not cause the entourage effect.

How to Vape CBD Isolate

Most people opt for CBD vapes since it is easier to regulate your dosage. Furthermore, they have a higher bioavailability, allowing you to experience CBD's therapeutic effects without much hassle.

Parts of a Vape Pen

The vape pen comprises an atomizer, a battery, a tank, and the CBD e-liquid. The atomizer heats the molecules inside the e-liquid while the battery powers up the vape pen. In addition, the tank stores the e-liquid, while the mouthpiece draws the vapour from the vape pen into the mouth and, consequently, into the lungs.

CBD isolate e-liquid contains two major chemical compounds for its efficacy. Vegetable glycerine (VG) is a thin, clear liquid with a slightly pleasant taste, while propylene glycol (PG) is a thinner liquid with an abstract taste

Vaping the CBD Isolate E-liquid

Most brands manufacture CBD isolate e-liquid to contain a 50PG/VG ratio, although sometimes it may be a 70PG/30VG ratio. This ensures that the e-liquid is as thin as possible for efficient heating in the vape pen.

While vaping, confirm whether the plus-ohm coil is above 1.0 ohms. Your device should have a lower wattage to prevent overheating the e-liquid. Therefore, -20W would be an ideal place to start.

You should also ensure that the heating coil is accurately soaked while filling your tank with CBD isolate e-liquid. Leaving the e-liquid to settle for about 10 minutes would be more efficient.

Place the vape pen onto your mouth, gently draw the vapour, and inhale it into your lungs. For proper absorption, ensure the CBD vapour remains in the lungs for a few seconds.

It is important to consult your doctor concerning the right CBD dosage to prevent unwarranted side effects. The dosage depends on your metabolism, weight, age, and tolerance. For example, if you have a higher metabolism, you may need more CBD to fully experience its effects since the body quickly uses CBD when consumed. In addition, people with a higher weight would require more CBD since it is a fat-soluble compound that can be stored in fat tissues after absorption.

You should ensure you are not allergic to propylene glycol (PG) since it may cause skin irritations. It would help if you also kept in mind the PG/VG ratio you want to use, depending on your unique body chemistry

Moreover, ensure you read the instructions on your vape pen before using it. You can also research online about the product and read the customer reviews to understand the product's efficacy.

What Type of Vape Pen Should You Use to Inhale CBD Isolate E-liquid?

Disposable and refillable CBD vape pens can equally do the trick, depending on your preferences. Disposable vape pens are often pre-filled with e-liquid and recharged since they can be discarded once the battery is depleted. They are more convenient since they are smaller, lighter, and easily portable. Disposable vape pens are highly recommended for beginners since they are more user-friendly. On the other hand, refillable vape pens are available in several shapes and sizes. The tank is empty, so you may have to buy a suitable e-liquid separately.

Benefits of Vaping CBD Isolate E-liquid

Below are the benefits of CBD isolate e-liquid;

  • Wang et al. (2020) stated that CBD has anti-inflammatory properties that alleviate muscle aches and inflammation.
  • According to Jastrząb et al. (2021), CBD has antioxidant properties that reduce oxidative stress in the muscles and tissues.
  • Calapai et al. (2019) explained that CBD has anti-anxiety properties that relieve anxiety, stress, and inflammation.
  • CBD also has the potential to improve heart health by reducing inflammation and stress, which cause higher blood pressure.
  • Udoh et al. (2022) stated that CBD has anticonvulsant properties that alleviate epileptic symptoms.

The Legality of CBD E-liquids

CBD was legalized in 2018 after Congress passed the Farm Bill. Hemp was removed from the Controlled Substances Act, and the definition of marijuana was revisited to exclude hemp extracts since they are non-psychoactive.

Although CBD e-liquids are legal under federal law, it is important to confirm their legality in your area since states were mandated to develop laws regulating the use of cannabidiol.

How to Purchase the Right CBD Isolate e-liquids

  • Confirm whether the CBD extract has undergone intensive independent third-party testing.
  • Ensure the CBD extract is obtained from organically grown hemp by confirming the hemp source.
  • Confirm the extraction method used to obtain the CBD extract. CO2 extraction is often preferred since it does not impurify the CBD extract.


CBD isolate e-liquids are considered the purest form of e-liquids since they only contain CBD as the primary chemical compound. Vaping e-liquids has become more popular in recent years since you can quickly experience CBD's therapeutic effects.

While vaping CBD e-liquids, ensure the device is at a low wattage to prevent overheating the e-liquid. Moreover, the plus-ohm coil should be above 1.0 ohms, and you should soak the coil in the e-liquid for about 10 minutes to guarantee efficacy.

CBD e-liquids have anti-inflammatory properties that alleviate inflammation. In addition, they have anti-anxiety properties that reduce stress, and they also have the potential to improve heart health while alleviating epileptic conditions. Ensure you purchase the right CBD e-liquids by confirming the hemp source and extraction methods and reading the customer reviews.


Calapai, G., Mannucci, C., Chinou, I., Cardia, L., Calapai, F., Sorbara, E. E., ... & Firenzuoli, F. (2019). Preclinical and clinical evidence supporting use of cannabidiol in psychiatry. Evidence-Based Complementary and Alternative Medicine2019.

Jastrząb, A., Jarocka-Karpowicz, I., Markowska, A., Wroński, A., Gęgotek, A., & Skrzydlewska, E. (2021). Antioxidant and anti-inflammatory effect of cannabidiol contributes to the decreased lipid peroxidation of keratinocytes of rat skin exposed to UV radiation. Oxidative Medicine and Cellular Longevity2021.

Udoh, M., Bladen, C., Heblinski, M., Luo, J. L., Janve, V. S., Anderson, L. L., ... & Arnold, J. C. (2022). The anticonvulsant phytocannabinoids CBGVA and CBDVA inhibit recombinant T-type channels. Frontiers in Pharmacology13, 1048259.

Wang, B., Kovalchuk, A., Li, D., Ilnytskyy, Y., Kovalchuk, I., & Kovalchuk, O. (2020). In search of preventative strategies: novel anti-inflammatory high-CBD cannabis sativa extracts modulate ACE2 expression in COVID-19 gateway tissues.