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How to Make Vape with CBD Isolate

December 19, 2022 5 min read

How to Make Vape with CBD Isolate

How to Make Vape with CBD Isolate

Do you know that you can make CBD vape juice from CBD isolate in a few simple steps? This article discusses how to make vape juice from CBD isolate, including the benefits of CBD vape juice.

Cannabidiol, or CBD, is a compound found in the cannabis plant. Cannabis has more than one hundred compounds known as cannabinoids. These compounds possess therapeutic properties that cannabis is widely associated with. Tetrahydrocannabinol, or THC and CBD, are the most popular cannabinoids with similar properties. Until recently, THC has been the most common cannabinoid used for both recreational and therapeutic purposes. However, scientists discovered that it is responsible for the intoxicating effects that people feel after using cannabis products. Unlike THC, CBD is non-intoxicating. For this reason, many people who want to try the therapeutic benefits of cannabis without experiencing mind-altering effects opt for CBD-based products like CBD vape juice. CBD vape oil contains CBD extract with other ingredients like vegetable glycerine, propylene glycerine, and flavorings.

How to Make Vape with CBD Isolate     

You can make a regular CBD vape juice with a few ingredients, whether an expert or a beginner; knowing how to make your e-liquid from CBD isolate will allow you to enjoy your vaping experience. The advantage of making your own CBD vape juice is that you have full control over the strength, flavor, and consistency.

What You Need

Vegetable Glycerine (VG) and Propylene Glycol (PG) or MTC Oil   

Vegetable glycerine (VG), or sugar alcohol, is among the key ingredients needed when making CBD vape. It is obtained by separating glycerine from the plant's fatty acids. VG is responsible for the thick vapor that many users love when vaping. Propylene glycol (PG) is more flavored and has a stronger throat hit than Manufacturers of CBD vape juice balance VG and PG to help users enjoy their vaping experience. MTC is an acronym for medium-chain triglyceride. MTC is a carrier oil mostly used as an alternative to propylene glycol and vegetable glycerine.Most vape juice manufacturers use MTC oil derived from coconut. MTC oil is usually flavorless and odorless, making it an excellent ingredient to include in your vape juice recipe.


CBD user users enjoy several flavorswhen vaping. When making your CBD vape juice, you have full control over the flavors obtained from either natural or artificial sources. Vape juice flavorsare never oil-based. Avoid flavorings made from essential oils since they can damage your health.


Terpenes are flavors or aromas naturally obtained from plants. They provide unique flavors and aromas normal flavors can bank on. Terpenes are also thought to help absorb cannabinoids by interacting with the endocannabinoid receptors, which is achieved throughthe "entourage effect."

CBD Extract (Isolate CBD) 

The last ingredient you will need is a CBD extract, isolate CBD. It is the purest type of CBD, with all other cannabinoids from the hemp plant filtered out. You can purchase your CBD isolate from trusted vape shops and retailers to ensure it is of the highest quality.


  • Put a considerable amount of PG into a clean container.
  • Add CBD isolate to the container.
  • Shake the container to mix the CBD isolate with PG until CBD isolate fully dissolves into PG and forms a consistent liquid.
  • Add VG and mix the components thoroughly until you obtain a uniform solution.
  • Add flavorings or terpenes and mix thoroughly with the rest of the solution.
  • Transfer the final solution into your vape tank and enjoy your vaping experience.

Benefits of CBD Vape Juice

Treat Chronic Inflammation

CBD's inflammatory properties can help people struggling with chronic inflammation and other inflammatory conditions. Brave (2019) stated that CBD  couldsignificantly reduce chronic pain and inflammation related to different health conditions, including arthritis and neurological and skin conditions.

It May Relieve the Side Effects of Chemotherapy

Cancer patients often experience unpleasant side effects that result from their cancer treatments. Ward et al. (2021) suggested that cannabinoids such as CBD can effectively regulate nausea, vomiting, and other adverse effects associated with cancer chemotherapy.

It May Enhance Sleep Quality

Insomnia and other sleep-related symptoms are major conditions affecting people's health. CBD vape juice could help with that too. While CBD vape juice may induce drowsiness in some users, it can also promote alertness in others. That makes it an excellent alternative treatment for people dealing with sleep-related issues.  Chagas et al. (2014) proved that cannabidiol could improve complex sleep-related behaviors associated with rapid eye movement and sleep disorders in Parkinson's patients.

Malka (2022) indicated that cannabinoids like CBD might reduce lung swelling and help open airways in people with chronic obstructive pulmonary disorder and asthma.

Other Benefits of Vaping CBD

  • CBD vape juice cannot get you high since it contains no THC, the main psychotropic compound of the cannabis plant.
  • Vaping provides the highest bioavailability of CBD. It delivers more CBD into the bloodstream than other methods of consuming CBD, such as oral ingestion.
  • Vaping is also the quickest way to feel the effects of cannabidiol. Most users report feeling the effects of CBD vape juice almost immediately after the first few puffs.
  • Vaping is a safer alternative to smoking.
  • CBD vape juice is available in various flavors that suit your preferences.


Although pre-mixed vape juice is extensively popular, some users love making their own. The guide above may be helpful to those who want to try DIY CBD vape juice. Making your own CBD vape product may not be smooth, especially for beginners. The process is more of trial and error until you find specific flavorings and PG/VG ration that suits your taste. Cannabidiol is generally safe and well-tolerated by most users. CBD vape juice comes with several health benefits.People use it to experience quick relief from their underlying medical issues. Always ensure your get your ingredients from a trusted and reputable supplier to get the best out of your CBD vape experience.


Brave, L. (2019). CBD affects the Skin, Mind, and Body. J Altern Complement Integr Med, 5, 060.

Chagas, M. H., Eckeli, A. L., Zuardi, A. W., Pena‐Pereira, M. A., Sobreira‐Neto, M. A., Sobreira, E. T., ... & Crippa, J. A. D. S. (2014). Cannabidiol can improve complex sleep‐related behaviors associated with rapid eye movement and sleep disorder in Parkinson's disease patients: a case series. Journal of clinical pharmacy and therapeutics, 39(5), 564-566.

Malka, D. Asthma, COPD & Medical Cannabis Asthma, COPD & Medical Cannabis.

Ward, S. J., Lichtman, A. H., Piomelli, D., & Parker, L. A. (2021). Cannabinoids and Cancer Chemotherapy-Associated Adverse Effects. Journal of the National Cancer Institute. Monographs, 2021(58), 78.