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How Long Does it Take for CBD Cream to Work?

December 19, 2022 5 min read

How Long Does it Take for CBD Cream to Work?

How Long Does it Take for CBD Cream to Work?

CBD cream may take ten to twenty minutes to work, although it varies from person to person. This article explains what CBD cream is, how long it takes to start working, factors affecting how long it starts working and how it makes individuals feel.

CBD cream has gained popularity in the recent world and is an amazing, natural way to relieve achy muscles and joints and treat arthritic pain. It offers immediate pain relief, which is why many individuals prefer it. It is a better alternative when treating pain in a localized area. Other CBD topicals that individuals use to reduce pain and treat skin conditions include CBD lotions, balms, salves, and gels. These methods are best for individuals who want to experience the benefits of CBD but do not want the bitter taste of CBD. Topical CBD does not enter the bloodstream. Individuals should not be worried whether it will show up on a drug test or make them high.

What Is CBD Cream?

This is like any other CBD cream but infused with CBD. It offers all the benefits the common cream offers with the additional benefits of CBD. It is applied directly into the skin and absorbed through the opened pores. They are available in three market types: broad-spectrum CBD creams, full-spectrum CBD creams, and CBD isolate creams. Full-spectrum CBD creams are considered the best and more effective for treating pain and skin conditions. They are only applied and massaged into the affected area. CBD cream has calming effects that make individuals relax after a long and tiring day. According to Henshaw et al. (2021), CBD also has anti-inflammatory that makes it ideal for treating skin conditions and pain. It is a cream many athletes use to reduce muscle and joint soreness after an active exercise.

How Long Does It Take for CBD Cream to Work?

Liu (2019) suggested that since CBD creams are applied directly to the skin, they get absorbed faster, and individuals start experiencing the benefits within ten to twenty minutes. However, this varies from individual to individual. Some people may start experiencing even two to three minutes after application, while others may wait longer to see the effects. According to Stella et al. (2021), CBD creams work by getting into subdermal and dermal layers under the skin and attaching to the cannabinoid receptors in the muscle and joints.  How individuals apply the cream plays a big role in how long the effects start kicking in. When users apply, slapping a thin layer of the cream and leaving it without even massaging will not have the same effects as the user who took his time to massage the cream well into the affected area. Massaging deeply into the skin tissues will enable CBD to penetrate quickly into the skin, accelerating the absorption rate in the endocannabinoid system (ECS). It is always good to massage the cream to the affected area to quickly see the results.

Factors Affecting How Long CBD Cream Takes to Work

Some factors affect how long CBD cream takes to work. One of them being the dosage individuals consume. Large dosages are likely to start working more quickly compared to small doses. However, individuals are advised to start at low dosages to see how the body and increase gradually when the body responds well. When the small dosages do not work for them, they should raise them.

How frequently individuals consume CBD also affects how long CBD cream takes to start working. The effects of CBD cream are likely to kick in quickly compared to new users or frequent users. This is because it may take some time for CBD to interact with the new user. This process may take longer for the new user to start feeling the effects of CBD. Solowij et al. (2019) claimed Consistency consumers could start experiencing CBD's benefits within 10 to 20 minutes.This varies from person to person. Some may experience instant relief, while others may take longer to experience the effects of CBD.

The quality of CBD used also contributes to how long CBD cream takes to work. Individuals should be aware that CBD products are not regulated. It is simple and easy to get a poor-quality product when not careful. Individuals should be careful when selecting any CBD product to get the best one. Individuals using a high-quality CBD cream will likely start experiencing the effects after ten to 20 minutes. However, a poor-quality product may fail to be effective or may take longer to start working. Individuals are advised to spend their money to buy a high-quality product that will be effective for them. Cheap price should not be one of the factors to consider when buying CBD products.

The body type and gender also affect how long CBD cream will take to start working. Greaves &Hemsing (2020) found that females are more responsive to CBD cream and other topicals than males. When women administer CBD cream directly to the skin, they can experience immediate relief from itching, inflammation, and pain. Most women have more fat than men. According to Franco et al. (2020), this makes them more receptive to CBD since it attaches to the fat to be absorbed into the system. CBD works better for individuals with large body fat.

The strength of CBD individuals uses also affects how long CBD cream takes to start working. Individuals who took strong CBD cream started experiencing the effects of CBD immediately. The weak CBD takes longer to kick in. Individuals should consider taking high-potency CBD to experience immediate relief.

How Does CBD Cream Make You Feel?

Oleinik (2022) found that CBD creams take about twenty minutes to start working. Individuals start experiencing the benefits of CBD, like muscle relaxation. Mental relaxation combines with physical relaxation since cannabidiol can alleviate anxiety and stress. Individuals begin experiencing relief from itching and inflammation. Individuals realize improvement in their skin. CBD creams treat skin conditions like eczema, psoriasis, rashes, inflammation, acne, and sunburn. CBD also reduces the signs of aging by eliminating wrinkles that give individuals a smooth and youthful appearance. It has moisturizing properties making skin look softer and more supple.


CBD creams take about 10 to 20 minutes; however, this varies from person to person. Some may start experiencing the effects of CBD 3 to 4 minutes after application, while others wait longer to see the effects. Individuals should massage the cream well into the affected area to experience the effects quickly. They should also purchase a CBD cream of high quality. This is because the poor-quality product may fail to be effective completely or may take longer to see effects and they made wear off more rapidly. Individuals should be careful when selecting CBD products since they are not regulated. However, it is a good idea to always consult the doctor before using any CBD product.


Franco, V., Gershkovich, P., Perucca, E., & Bialer, M. (2020). The interplay between liver first-pass effect and lymphatic absorption of cannabidiol and its implications for cannabidiol oral formulations. Clinical Pharmacokinetics, 59(12), 1493-1500.

Henshaw, F. R., Dewsbury, L. S., Lim, C. K., & Steiner, G. Z. (2021). The effects of cannabinoids on pro-and anti-inflammatory cytokines: a systematic review of in vivo studies. Cannabis and Cannabinoid Research, 6(3), 177-195.

Stella, B., Baratta, F., Della Pepa, C., Arpicco, S., Gastaldi, D., & Dosio, F. (2021). Cannabinoid formulations and delivery systems: Current and future options to treat pain. Drugs, 81(13), 1513-1557.

Oleinik, G. The Best CBD Creams & Topicals for Acne (March 2022).