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How Does CBD Pain Cream Work?

December 17, 2022 4 min read

How Does CBD Pain Cream Work?

How Does CBD Pain Cream Work?

CBD cream is used for different benefits, including pain management. This article explains how CBD pain cream works, and the benefits of this product.

Cannabis Sativa plants produce hundreds of different biological active ingredients, with CBD among its most active alongside THC. Unlike CBD, THC makes people high. Studies show that CBD can ease pain without the euphoria brought about by THC or the fear of addiction. Pain has always been a problem, and many people, when opioids, most of them are addictive, don’t work, end up using heroin. CBD provides a safer alternative to pharmacological drugs. CBD is becoming popular for self-medicated health conditions. Those who use it for pain relief claim it has a lot of benefits.

What Is CBD Skin Cream?

Lotions and oils are added to CBD hemp seed oil or other products to make the Cannabidiol-infused cream; the cannabis derivative has a lot of benefits, mainly alleviating pain and inflammation in different body parts. The cannabis-infused cream targets the joints. Shao, Stewart, & Grant-Kels (2021) indicated that CBD creams which help with inflammation, could also treat acne, psoriasis, and eczema. The cream and lotions can provide relief both at the surface and deeper muscle levels. Some people claim that they aid relaxation, which helps individuals to sleep. CBD creams are an alternative to edibles infused with cannabis; the products also offer anti-inflammatory or muscle pain. A person new to CBD products should consider using a small amount before increasing to the desired effect.

What Research Says About CBD and Pain?

Khaleghi (2020) indicated that CBD cream could alleviate pain regarding arthritis, inflammation, and chronic pain. However, most CBD studies have primarily been done on animals. CBD has also appeared to trend in health care and skin care. But an increasing number of people are now using CBD to manage chronic pain, arthritis, or joint pain. Does it produce the desired effect?

Less has been done to research CBD and how it alleviates human pain. CBD balms and creams are referred to as topicals. Topicals are just a classification of CBD products made for the skin. The skin can absorb nutrients from the topical, which will get their way to the bloodstream and the surrounding area. Topical CBD products address pain or inflammation in specific body areas, a good example being the joints. 

Historically, CBD has been used in ancient China, India, and Latin America in treating various skin conditions as a natural remedy. Recently, it was re-established as a natural remedy for pain and inflammation. 

Unlike THC, CBD does not have adverse side effects. In the UK, any CBD product should not contain more than 1mg of THC. Legal CBD products do not make one high. When used on the skin, it eases pain without masking its causes or inflammation. Our body naturally contains cannabinoid receptors, which absorb CBD products to alleviate pain in the intended body part. The Endocannabinoid system has enzymes, endocannabinoids, and cannabinoid receptors (such as CB1 and CB2 receptors). The system ensures that the body always returns to a stable state in case of an imbalance caused by pain. It is responsible for actions like sweating, digestion, and pain perception. Many people have testified that CBD products reduce.

How CBD Works to Reduce Pain

The nervous system transmits pain from one area to the brain. Pain affects a lot of interaction and interferes with activities like sports and mobility. CBD manages pain by blocking sensations within the nerve. A lot of pain we experience is caused by body inflammation. The Endocannabinoid system is responsible for pain and pleasure. Using the ECS, cannabinoids can respond by managing the inflammation in the body. CBD works by stimulating receptors CB1 and CB2, which enables it to manage pain and inflammation. Researchers think CBD oil or cream stimulates the body to use its endocannabinoids more effectively to block pain. CBD cream cannot penetrate thick skin into the bloodstream.CBD does not have adverse side effects. Instead, it is a moisturizer. 

Benefits of CBD creams

Shao, Stewart, & Grant-Kels (2021) explained that CBD topical had been shown to treat skin problems, localized pain, and inflammation; this reduces pain and psychological effects, helping users sleep. CBD creams work better than those orally ingested. They are applied directly to the area where the effect is required. They don’t make people high because topical CBD does not enter the bloodstream. When one uses cannabis-infused creams, one need not worry about failing a drug test. CBD creams inhibit the build-up of dead cells and soothe pain caused by various skin infections. Perez et al. (2022) observed that CBD contains medicinal and anti-aging properties that make the skin appear smooth and youthful. Curcio (2021) mentioned that CBD creams are recommended to improve muscle aches and the rate of muscle recovery; this allows the muscles to stop aching. It supports faster recovery between workouts or following injury.


CBD topicals come in different strengths, effective for treating various skin conditions. The dosages of CBD topicals are also very different for everyday topical products. However, one should start slow and increase the dose until one gets the desired effects. Cannabidiol products are effective alongside other strategies like rest to enhance the therapeutic benefits experienced by the products. You should also consult your doctor to give further direction on the usage of CBD products.


Curcio, A., Nano, F., Pironti, M., Marchitto, N., Pannozzi, A., &Bilo, L. L. (2021). In vitro Study Evaluating the Influence of Vehicle in the Permeability Process of a Topical Composition Containing Cannabis Sativa Oil, Escin, Bromelain, Glucosamine Sulphate, Methylsulfonylmethane, Methylsalicylate and Boswellia Extract, Designed for Local Treatment of Musculoskeletal Painful and Inflammatory Conditions. J ClinChem Lab Med4, 188.

Khaleghi, M. (2020). New arthritis foundation guidelines on CBD use could be first of many more to come. Alternative therapies in health and medicine26, 8-11.

Perez, E., Fernandez, J. R., Fitzgerald, C., Rouzard, K., Tamura, M., & Savile, C. (2022). In Vitro and Clinical Evaluation of Cannabigerol (CBG) Produced via Yeast Biosynthesis: A Cannabinoid with a Broad Range of Anti-Inflammatory and Skin Health-Boosting Properties. Molecules27(2), 491.

Piermarini, C., &Viswanath, O. (2019). CBD as the New Medicine in the Pain Provider’s Armamentarium. Pain and Therapy8(1), 157-158.

Shao, K., Stewart, C., & Grant-Kels, J. M. (2021). Cannabis and the skin. Clinics in Dermatology39(5), 784-795.